The 22nd Princeton Conference on Cerebrovascular Disease, held in Redwood City, California, 10–12 March 2000, was hosted by the Stanford University School of Medicine, with administrative support provided by the Neurosurgical Laboratories, Department of Neurosurgery. The Conference focused on the current status and future directions of stroke pathophysiology, diagnosis and treatment, with special emphasis on the cellular and molecular mechanisms of ischemic cell death and repair, and clini ...